BIOTECHNOLOGY; HEALTH ENTERPRISE MANAGEMENT
Director and Clincal Professor of Biotechnology
Dr. Löffler served as advisor of: Baird Venture Partners; founding Board Member of the Biotechnology Institute, Washington DC; Biopharmaceutical Center at the WHU in Koblenz, Germany and multiple biotechnology companies. She consulted extensively on technology assessment issues for major pharmaceutical companies and Universities in the US. She also served at as the Board Member and Past-Chair, Council for Biotechnology Centers (BIO), and Board Member, Emerging Companies, Biotechnology Industry Organization and the Governor’s Edgar Council for Biotechnology. She was recently named one of the Tech 100 stars by Crain’s Chicago Business and received the “Women in Black” I-Street award. She is completing her second book, Rethinking the Biotechnology Model. Dr. Löffler received her BS from the University of Minnesota, Ph.D from the University of Massachusetts and post-doctoral in biochemical engineering from Caltech.
Technology Assessments (Biotechnology)
Innovation
Strategic Assessment
- Recent Media Coverage
Medill Reports: Medical experts say U.S. innovation needs a nudge - 4/16/2009
Crain's Chicago Business: Medical startups — for credit - 9/3/2007
See all Kellogg in the Media
- Recent Kellogg News
Kellogg biotechnology competition draws global interest - 12/10/2008
See all Kellogg News
Book Chapter - This Chapter explores the international structure of the biotech innovation process, discusses causes, quantitative measures to track international trends and impact on the firm, industry and US public policy
Published Study by the NYSE- This study makes the case for fundamental changes in the biomedical industry in the coming years. It predicts the ascendance of personalized medicine and sdescribes how the biomedical industry players will need to adapt to profound demographic, political and technological shifts in order to compete successfully in a world transformed by globalization forces.
This report for the Bureau of Labor Statistics provides a systematic evaluation and framework for occupation categories and industry structure in the biotechnology industry.
This report for the Bureau of Labor Statistics provides a systematic evaluation and framework for occupation categories and industry structure in the biotechnology industry.
Edited series of students articles from Tech ventures
The case explores the decision facing Gilead’s CEO to donate and distributing HIV drugs to Africa. The company is small and does not have profits and ,unlike the pharmaceutical giants, does not have an established access program. The case explores the tensions between stakeholders, shareholders and employees. Does Gilead have an obligation to sell its life-saving medication in every country that needs it? Even if it decides to go ahead with the access program in Africa, the stakes for the company are much higher than just distributing the drugs. The country’s infrastructure to provide education and access to affordable drugs is not sufficient enough. There is no guarantee that the drugs will reach the patients or sit in a warehouse for months. If it does reach the patients, how much of drug should be supplied at a time to prevent black marketing. . Dealing with the AIDS activist will be a human nightmare. As the CEO of Gilead, he has to make a decision that will satisfy the company’s board members, stockholders, employees and the public.
In the year 2000 Millennium Pharmaceuticals was the poster child for successful genomic companies. Millennium's fast growth and exuberant valuations were due to the elegant alliances the company had forged with top pharmaceutical, biotechnology, and agricultural companies. However as the market shifted and Millennium was forced to fully integrate, the type and structure of its alliances no longer worked. This case illustrates how strategic alliances are used in biotechnology as growth tools and demonstrates the impact that market conditions can have on the evolution of alliances.
Immunex, a small Seattle biotechnology company, stumbles into a hugely successful and groundbreaking product. Enbrel, a tumor necrosis factor, is immediately recognized as the most effective treatment for rheumatoid arthritis-a $300 billion market in the United States. After almost 20 years of unprofitability, Enbrel is a lifesaver for Immunex. But it could also become the company's worst nightmare. Immunex, after years of being cash-starved, has not been able to build production capabilities to satisfy the sudden and massive demand for its drug. This case illustrates the decision-making process on how and when to build commercialization capabilities in a small biotechnology company. In addition it explores options for reacting to an unexpected demand in a hypercompetitive market.
This case describes the growth of a biotechnology company as it shifts from a service research organization to an integrated human therapeutic company. The case maps the management changes from 1982-1998 as the company responds to volatile market pressures. Survivor Scios can be used to illustrate the challenges of shifting strategies in a research intensive organization. In addition it can be used to point up the different management styles needed at different stages of a company's life cycle. Finally the case demonstrates the unique issues of product development in a biotechnology firm.
This course counts toward the following majors: Health Enterprise Management, Health Industry Management
Although this course is intended primarily for first-year students majoring in health industry management, all students with an interest in this sector are encouraged to enroll. It is particularly useful for students interested in pharmaceuticals, biotechnology and medical devices, who need to understand not only how their sector fits into the industry but also how their customers are paid and how they use their products. The course introduces students to the key issues confronting the major participants in the U.S. health system (suppliers, providers and payers). Topics covered include a framework for evaluating healthcare systems, understanding the demand for healthcare products and services, technology assessment, managed care systems, cost/quality issues and payment mechanisms.
Biotech Business Practicum (formerly BIOT-913-0) (HEMA-913-0)
This course counts toward the following majors: Biotechnology Management, Health Enterprise Management
Biotechnology demands depth of knowledge and hands-on experience from its managers. Biotech Business Practicum gives you an opportunity to apply the theoretical concepts you learned in class with the real, practical needs of the biotechnology firm. Students, individually or as part of a team, work on a project for a biotech, pharmaceutical, medical device or venture capital concern under the mentorship of a Kellogg faculty member and an industrial mentor.
Medical Innovation I (HEMA-915-0)
This course counts toward the following majors: Biotechnology Management, Health Enterprise Management,
Medical Innovation is a two-quarter sequence focused on the creation of innovations for the health industry. Students, guided by faculty and physicians from Kellogg and the Northwestern law, medical and engineering schools work in teams to develop medical products. Students experience the entire innovation life cycle from ideation to prototyping, legal protection, market sizing and business plan development. At the end of the course, the teams present their business plans to a panel of venture capitalists with the goal of securing funding and possible formation of a start-up. Key deliverables in this class include: “elevator pitch” to request prototype/pilot funding, prototype development, provisional patent application, FDA 510/K application and business plan presentation to venture capitalists. To enroll in this course, permission from the instructor is required before registration. Students must take both the fall (I) and winter (II) quarter courses, in sequence, and will earn 2.0 credits after successfully completing both courses.
Medical Innovation II: Developing Biomedical Products from Patient to Market (formerly BIOT-916-0) (HEMA-916-0)
This course counts toward the following majors: Biotechnology Management, Health Enterprise Management
Medical Innovation is a two-quarter sequence focused on the creation of innovations for the health industry. Students, guided by faculty and physicians from Kellogg and the Northwestern law, medical and engineering schools work in teams to develop medical products. Students experience the entire innovation life cycle from ideation to prototyping, legal protection, market sizing and business plan development. At the end of the course, the teams present their business plans to a panel of venture capitalists with the goal of securing funding and possible formation of a start-up. Key deliverables in this class include: “elevator pitch” to request prototype/pilot funding, prototype development, provisional patent application, FDA 510/K application and business plan presentation to venture capitalists. To enroll in this course, permission from the instructor is required before registration. Students must take both the fall and winter quarter courses, in sequence, and will earn 2.0 credits after successfully completing both courses.
This course focuses on the process of bringing life science innovations to the market. We start with an overview of the life science industry’s environment including dynamics, drivers, context for innovation, and value propositions. We will then explore how to best capture value from innovation by analyzing different industry cases. Finally we will work on developing a business case from a life science innovation.
PHONE: 847-467-1453
FAX: 847-467-2180
Jacobs Center Room 5214